Also wenn das nicht der Plot des Jahres ist:
THE HUMAN CENTIPEDE is an unconventional – and medically accurate — biological horror film that enthusiastically explores territory that few filmmakers dare to tread. When two pretty American girls go on a road trip in Europe, they end up alone at night in Germany with a broken car in the woods. They search for help and find an isolated villa, and awake the next day to find themselves trapped in a terrifying makeshift basement hospital. Their captor is the internationally respected Siamese twin surgeon Dr. Josef Heiter with a demented vision for mankind’s future existence. Dr. Heiter wants to remove human beings’ kneecaps so they have to exist on all fours and then surgically graft them mouth-to-anus to form a centipede chain. But when his victims give him more trouble than he expects – including unwanted attention from the authorities – Dr. Heiter is forced to decide whether to abandon his latest project, or protect it from the outside world – with their and his very lives, if necessary.